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From in vivo to in vitro: Major metabolic alterations take place in hepatocytes during and following isolation
The liver plays a key role in maintaining physiological homeostasis and hepatocytes are largely responsible for this. The use of isolated primary hepatocytes has become an essential tool for the study of nutrient physiology, xenobiotic metabolism and several liver pathologies. Since hepatocytes are...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746264/ https://www.ncbi.nlm.nih.gov/pubmed/29284039 http://dx.doi.org/10.1371/journal.pone.0190366 |