Single-cell RNA sequencing reveals intrinsic and extrinsic regulatory heterogeneity in yeast responding to stress

From bacteria to humans, individual cells within isogenic populations can show significant variation in stress tolerance, but the nature of this heterogeneity is not clear. To investigate this, we used single-cell RNA sequencing to quantify transcript heterogeneity in single Saccharomyces cerevisiae...

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Detalles Bibliográficos
Autores principales: Gasch, Audrey P., Yu, Feiqiao Brian, Hose, James, Escalante, Leah E., Place, Mike, Bacher, Rhonda, Kanbar, Jad, Ciobanu, Doina, Sandor, Laura, Grigoriev, Igor V., Kendziorski, Christina, Quake, Stephen R., McClean, Megan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746276/
https://www.ncbi.nlm.nih.gov/pubmed/29240790
http://dx.doi.org/10.1371/journal.pbio.2004050

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