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Polypyridylruthenium(II) complexes exert anti-schistosome activity and inhibit parasite acetylcholinesterases
BACKGROUND: Schistosomiasis affects over 200 million people and there are concerns whether the current chemotherapeutic control strategy (periodic mass drug administration with praziquantel (PZQ)—the only licenced anti-schistosome compound) is sustainable, necessitating the development of new drugs....
Autores principales: | Sundaraneedi, Madhu K., Tedla, Bemnet A., Eichenberger, Ramon M., Becker, Luke, Pickering, Darren, Smout, Michael J., Rajan, Siji, Wangchuk, Phurpa, Keene, F. Richard, Loukas, Alex, Collins, J. Grant, Pearson, Mark S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746282/ https://www.ncbi.nlm.nih.gov/pubmed/29240773 http://dx.doi.org/10.1371/journal.pntd.0006134 |
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