Combination treatment of adipose-derived stem cells and adiponectin attenuates pulmonary arterial hypertension in rats by inhibiting pulmonary arterial smooth muscle cell proliferation and regulating the AMPK/BMP/Smad pathway

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The present study aimed to assess the effects of therapy with adiponectin (APN) gene-modified adipose-derived stem cells (ADSCs) on pulmonary arterial hypertension (PAH) in rats and the underlying cellular and molecular mechanisms. ADSCs were successfully isolated from the rats and characterized. AD...

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Detalles Bibliográficos
Autores principales: Luo, Li, Zheng, Wuhong, Lian, Guili, Chen, Huaning, Li, Ling, Xu, Changsheng, Xie, Liangdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746303/
https://www.ncbi.nlm.nih.gov/pubmed/29115380
http://dx.doi.org/10.3892/ijmm.2017.3226
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