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Fibroblast activation protein-α promotes the growth and migration of lung cancer cells via the PI3K and sonic hedgehog pathways

A characteristic of the epithelial-to-mesenchymal transition in cancer cells is the upregulation of mesenchymal markers. Fibroblast activation protein α (FAPα) is predominantly expressed by stromal fibroblasts. Previous studies have demonstrated that FAPα is also expressed by certain epithelium-deri...

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Detalles Bibliográficos
Autores principales: Jia, Jun, Martin, Tracey A., Ye, Lin, Meng, Lin, Xia, Nan, Jiang, Wen G., Zhang, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746330/
https://www.ncbi.nlm.nih.gov/pubmed/29115573
http://dx.doi.org/10.3892/ijmm.2017.3224

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