Identifying mitotane-induced mitochondria-associated membranes dysfunctions: metabolomic and lipidomic approaches

Mitotane (o,p’DDD), the most effective drug in adrenocortical carcinoma, concentrates into the mitochondria and impacts mitochondrial functions. To address the molecular mechanisms of mitotane action and to identify its potential target, metabolomic and lipidomic approaches as well as imaging analys...

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Detalles Bibliográficos
Autores principales: Hescot, Ségolène, Amazit, Larbi, Lhomme, Marie, Travers, Simon, DuBow, Anais, Battini, Stephanie, Boulate, Geoffrey, Namer, Izzie Jacques, Lombes, Anne, Kontush, Anatol, Imperiale, Alessio, Baudin, Eric, Lombes, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746354/
https://www.ncbi.nlm.nih.gov/pubmed/29299119
http://dx.doi.org/10.18632/oncotarget.18968

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