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Wnt/β-catenin and Hedgehog pathways are involved in the inflammatory effect of Interleukin 18 on rat chondrocytes

To investigate the inflammatory effect of Interleukin 18 (IL-18) on rat chondrocytes and the involvement of Wnt/β-catenin and Hedgehog pathways, the mRNA and protein level of matix-degrading enzymes (MMP-2, 3, 9,13 and aggrecanses) and chondrocyte-specific proteins (Collagen II and aggrecan) were ev...

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Detalles Bibliográficos
Autores principales: Bao, Jiapeng, Ma, Chiyuan, Ran, Jisheng, Xiong, Yan, Yan, Shigui, Wu, Lidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746357/
https://www.ncbi.nlm.nih.gov/pubmed/29299122
http://dx.doi.org/10.18632/oncotarget.20584