Strong fascin expression promotes metastasis independent of its F-actin bundling activity

High expression of the actin bundling protein Fascin increases the malignancy of tumor cells. Here we show that fascin expression is up-regulated in more malignant sub-cell lines of MDA-MB-231 cells as compared to parental cells. Since also parental MDA-MB-231 cells exhibit high fascin levels, incre...

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Detalles Bibliográficos
Autores principales: Heinz, Lisa S., Muhs, Stefanie, Schiewek, Johanna, Grüb, Saskia, Nalaskowski, Marcus, Lin, Yuan-Na, Wikman, Harriet, Oliveira-Ferrer, Leticia, Lange, Tobias, Wellbrock, Jasmin, Konietzny, Anja, Mikhaylova, Marina, Windhorst, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746366/
https://www.ncbi.nlm.nih.gov/pubmed/29299131
http://dx.doi.org/10.18632/oncotarget.22249

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