Domain retention in transcription factor fusion genes and its biological and clinical implications: a pan-cancer study

Genomic rearrangements involving transcription factors (TFs) can form fusion proteins resulting in either enhanced, weakened, or even loss of TF activity. Functional domain (FD) retention is a critical factor in the activity of transcription factor fusion genes (TFFGs). A systematic investigation of...

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Detalles Bibliográficos
Autores principales: Kim, Pora, Ballester, Leomar Y., Zhao, Zhongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746368/
https://www.ncbi.nlm.nih.gov/pubmed/29299133
http://dx.doi.org/10.18632/oncotarget.22653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746368/
https://www.ncbi.nlm.nih.gov/pubmed/29299133
http://dx.doi.org/10.18632/oncotarget.22653

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