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Targeting chaperonin containing TCP1 (CCT) as a molecular therapeutic for small cell lung cancer

Identifying new druggable targets is desired to meet the needs for effective cancer treatments. To this end, we previously reported the efficacy of a therapeutic peptide called CT20p that displays selective cytotoxicity through inhibition of a multi-subunit, protein-folding complex called Chaperonin...

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Detalles Bibliográficos
Autores principales: Carr, Ana C., Khaled, Amr S., Bassiouni, Rania, Flores, Orielyz, Nierenberg, Daniel, Bhatti, Hammad, Vishnubhotla, Priya, Manuel, J. Perez, Santra, Santimukul, Khaled, Annette R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746381/
https://www.ncbi.nlm.nih.gov/pubmed/29299146
http://dx.doi.org/10.18632/oncotarget.22681