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Neuroprotection by aripiprazole against β-amyloid-induced toxicity by P-CK2α activation via inhibition of GSK-3β
Psychosis is reported over 30% of patients with Alzheimer's disease (AD) in clinics. Aripiprazole is an atypical antipsychotic drug with partial agonist activity at the D(2) dopamine and 5-HT(1A) receptors with low side-effect profile. We identified aripiprazole is able to overcome the amyloid-...
Autores principales: | Park, So Youn, Shin, Hwa Kyoung, Lee, Won Suk, Bae, Sun Sik, Kim, Koanhoi, Hong, Ki Whan, Kim, Chi Dae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746390/ https://www.ncbi.nlm.nih.gov/pubmed/29299155 http://dx.doi.org/10.18632/oncotarget.22777 |
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