Cargando…

Smad1 promotes colorectal cancer cell migration through Ajuba transactivation

SMAD family member 1 (Smad1) have been involved in metastatic progression of many cancer types. However, the detailed molecular signalling pathway underlying the regulatory link between Smad1 and metastasis remains elusive. Here, we demonstrate that Smad1 promotes migration of colorectal cancer (CRC...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Daming, Hou, Tieying, Li, Lei, Chu, Yimin, Zhou, Fengli, Xu, Ying, Hou, Xinyu, Song, Huan, Zhu, Kai, Hou, Zhaoyuan, Peng, Haixia, Jia, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746393/ https://www.ncbi.nlm.nih.gov/pubmed/29299158 http://dx.doi.org/10.18632/oncotarget.22780

Ejemplares similares

Ajuba transactivates N‐cadherin expression in colorectal cancer cells through interaction with Twist
por: Wu, Zhaoxia, et al.
Publicado: (2021)

The LIM protein Ajuba/SP1 complex forms a feed forward loop to induce SP1 target genes and promote pancreatic cancer cell proliferation
por: Zhang, Bosen, et al.
Publicado: (2019)

The LIM protein Ajuba recruits DBC1 and CBP/p300 to acetylate ERα and enhances ERα target gene expression in breast cancer cells
por: Xu, Beihui, et al.
Publicado: (2019)

Ajuba is required for Rac activation and maintenance of E-cadherin adhesion
por: Nola, Sébastien, et al.
Publicado: (2011)

The LIM Protein Ajuba Augments Tumor Metastasis in Colon Cancer
por: Dommann, Noëlle, et al.
Publicado: (2020)

AJUBA promotes the migration and invasion of esophageal squamous cell carcinoma cells through upregulation of MMP10 and MMP13 expression
por: Shi, Xuejiao, et al.
Publicado: (2016)

The LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migration
por: Pratt, Stephen J., et al.
Publicado: (2005)

USP37 Promotes Lung Cancer Cell Migration by Stabilizing Snail Protein via Deubiquitination
por: Cai, Jiali, et al.
Publicado: (2020)

FoxM1 transactivates PTTG1 and promotes colorectal cancer cell migration and invasion
por: Zheng, Yun, et al.
Publicado: (2015)

Analysis of transcript-wide profile regulated by microsatellite instability of colorectal cancer
por: Xu, Ying, et al.
Publicado: (2022)

LIM Protein Ajuba Participates in the Repression of the ATR-Mediated DNA Damage Response
por: Kalan, Sampada, et al.
Publicado: (2013)

The force-sensitive protein Ajuba regulates cell adhesion during epithelial morphogenesis
por: Razzell, William, et al.
Publicado: (2018)

Analysis of the Drosophila Ajuba LIM protein defines functions for distinct LIM domains
por: Rauskolb, Cordelia, et al.
Publicado: (2022)

AJUBA and WTIP can compete with LIMD1 for junctional localization and LATS regulation
por: Kirichenko, Elmira, et al.
Publicado: (2022)

FOXM1 promotes invasion and migration of colorectal cancer cells partially dependent on HSPA5 transactivation
por: Luo, Xiaoyong, et al.
Publicado: (2016)

Hsa_circ_0128846 promotes tumorigenesis of colorectal cancer by sponging hsa‐miR‐1184 and releasing AJUBA and inactivating Hippo/YAP signalling
por: Wang, Xu, et al.
Publicado: (2020)

Super-enhancer-driven AJUBA is activated by TCF4 and involved in epithelial-mesenchymal transition in the progression of Hepatocellular Carcinoma
por: Zhang, Chi, et al.
Publicado: (2020)

GATA zinc finger protein p66β promotes breast cancer cell migration by acting as a co-activator of Snail
por: Zou, Xiuqun, et al.
Publicado: (2023)

Peripodial adherens junctions regulate Ajuba-Yorkie signaling to preserve fly eye morphology
por: DeSantis, Dana F., et al.
Publicado: (2023)

LHPP suppresses colorectal cancer cell migration and invasion in vitro and in vivo by inhibiting Smad3 phosphorylation in the TGF-β pathway
por: Hou, Bin, et al.
Publicado: (2021)

The LIM Protein AJUBA is a Potential Oncogenic Target and Prognostic Marker in Human Cancer via Pan-Cancer Analysis
por: Song, Na, et al.
Publicado: (2022)

LIM domain‐containing protein Ajuba inhibits chemotherapy‐induced apoptosis by negatively regulating p53 stability in colorectal cancer cells
por: Xu, Beihui, et al.
Publicado: (2023)

Ajuba Overexpression Promotes Breast Cancer Chemoresistance and Glucose Uptake through TAZ-GLUT3/Survivin Pathway
por: Li, Xiang, et al.
Publicado: (2022)

TGF‐β transactivates EGFR and facilitates breast cancer migration and invasion through canonical Smad3 and ERK/Sp1 signaling pathways
por: Zhao, Yuanyuan, et al.
Publicado: (2018)

The crescent-like Golgi ribbon is shaped by the Ajuba/PRMT5/Aurora-A complex-modified HURP
por: Chiu, Shao-Chih, et al.
Publicado: (2023)

IL-8-mediated overexpression of ZNF274 promotes the proliferation and migration of colorectal cancer cells through the transactivation of MRPL40
por: Du, Feng, et al.
Publicado: (2023)

Ajuba receptor mediates the internalization of tumor-secreted GRP78 into macrophages through different endocytosis pathways
por: La, Xiaoqin, et al.
Publicado: (2018)

The scaffold protein Ajuba suppresses CdGAP activity in epithelia to maintain stable cell-cell contacts
por: McCormack, J. J., et al.
Publicado: (2017)

MiRNA-21 promotes differentiation of bone marrow mesenchymal stem cells into cardiomyocyte-like cells by regulating the Ajuba/Isl1 axis pathway
por: Yang, Wengang, et al.
Publicado: (2022)

AJUBA LIM Proteins Limit Hippo Activity in Proliferating Cells by Sequestering the Hippo Core Kinase Complex in the Cytosol
por: Jagannathan, Radhika, et al.
Publicado: (2016)

Correction: Transcriptional factors Smad1 and Smad9 act redundantly to mediate zebrafish ventral specification downstream of Smad5.
por: Wei, Chang-Yong, et al.
Publicado: (2021)

Correction: Transcriptional factors smad1 and smad9 act redundantly to mediate zebrafish ventral specification downstream of smad5
por: Wei, Chang-Yong, et al.
Publicado: (2021)

LIM Protein Ajuba associates with the RPA complex through direct cell cycle-dependent interaction with the RPA70 subunit
por: Fowler, Sandy, et al.
Publicado: (2018)

The SQSTM1/p62 UBA domain regulates Ajuba localisation, degradation and NF-κB signalling function
por: Sultana, Melanie A., et al.
Publicado: (2021)

MiR-144 suppresses cell proliferation, migration, and invasion in hepatocellular carcinoma by targeting SMAD4
por: Yu, Min, et al.
Publicado: (2016)

Case Report: Identification of a novel NTRK3-AJUBA fusion co-existing with ETV6-NTRK3 fusion in papillary thyroid carcinoma
por: Yu, Qing-Xiang, et al.
Publicado: (2023)

Transactivation of proto-oncogene c-Myc by hepatitis B virus transactivator MHBs(t167)
por: LUN, YONG-ZHI, et al.
Publicado: (2014)

Swimming Impedes Intestinal Microbiota and Lipid Metabolites of Tumorigenesis in Colitis-Associated Cancer
por: Wang, Weiyi, et al.
Publicado: (2022)

Dihydroartemisinin inhibits endothelial cell migration via the TGF-β1/ALK5/SMAD2 signaling pathway
por: Guo, Ling, et al.
Publicado: (2021)

Comprehensive analysis of HOXC8 associated with tumor microenvironment characteristics in colorectal cancer
por: Wu, Sifan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_7cnetaaethp9e1h65l131mklnc