Lactate-activated macrophages induced aerobic glycolysis and epithelial-mesenchymal transition in breast cancer by regulation of CCL5-CCR5 axis: a positive metabolic feedback loop

Aberrant energy metabolism is critical for cancer progression. Tumor-associated macrophages (TAMs) can stimulate tumor angiogenesis and enhance cancer metastasis; however, the metabolic interaction between cancer cells and macrophages characterized by lactate shuttles remains unclear. Here, we showe...

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Detalles Bibliográficos
Autores principales: Lin, Sensen, Sun, Li, Lyu, Xiaodan, Ai, Xiongfei, Du, Danyu, Su, Nan, Li, Hongyang, Zhang, Luyong, Yu, Jun, Yuan, Shengtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746394/
https://www.ncbi.nlm.nih.gov/pubmed/29299159
http://dx.doi.org/10.18632/oncotarget.22786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746394/
https://www.ncbi.nlm.nih.gov/pubmed/29299159
http://dx.doi.org/10.18632/oncotarget.22786

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