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Lactate-activated macrophages induced aerobic glycolysis and epithelial-mesenchymal transition in breast cancer by regulation of CCL5-CCR5 axis: a positive metabolic feedback loop

Aberrant energy metabolism is critical for cancer progression. Tumor-associated macrophages (TAMs) can stimulate tumor angiogenesis and enhance cancer metastasis; however, the metabolic interaction between cancer cells and macrophages characterized by lactate shuttles remains unclear. Here, we showe...

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Detalles Bibliográficos
Autores principales:	Lin, Sensen, Sun, Li, Lyu, Xiaodan, Ai, Xiongfei, Du, Danyu, Su, Nan, Li, Hongyang, Zhang, Luyong, Yu, Jun, Yuan, Shengtao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746394/ https://www.ncbi.nlm.nih.gov/pubmed/29299159 http://dx.doi.org/10.18632/oncotarget.22786

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