C21 steroid-enriched fraction refined from Marsdenia tenacissima inhibits hepatocellular carcinoma through the coordination of Hippo-Yap and PTEN-PI3K/AKT signaling pathways

Marsdenia tenacissimae extraction (MTE), a traditional herbal medicine, has exhibited anti-tumor effects on a variety of cancers. However, its effectiveness and the mechanism of action in Hepatocellular carcinoma (HCC) has not been fully understood. In the present study, we demonstrate that C21 ster...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Li, Kaiqiang, Ying, Youmin, Chen, Bingyu, Hao, Ke, Chen, Boxu, Zheng, Yu, Lyu, Jianxin, Tong, Xiangming, Chen, Xiaopan, Wang, Ying, Zhan, Zhajun, Zhang, Wei, Wang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746405/
https://www.ncbi.nlm.nih.gov/pubmed/29299170
http://dx.doi.org/10.18632/oncotarget.22833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746405/
https://www.ncbi.nlm.nih.gov/pubmed/29299170
http://dx.doi.org/10.18632/oncotarget.22833

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