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C21 steroid-enriched fraction refined from Marsdenia tenacissima inhibits hepatocellular carcinoma through the coordination of Hippo-Yap and PTEN-PI3K/AKT signaling pathways
Marsdenia tenacissimae extraction (MTE), a traditional herbal medicine, has exhibited anti-tumor effects on a variety of cancers. However, its effectiveness and the mechanism of action in Hepatocellular carcinoma (HCC) has not been fully understood. In the present study, we demonstrate that C21 ster...
Autores principales: | Zhang, Yu, Li, Kaiqiang, Ying, Youmin, Chen, Bingyu, Hao, Ke, Chen, Boxu, Zheng, Yu, Lyu, Jianxin, Tong, Xiangming, Chen, Xiaopan, Wang, Ying, Zhan, Zhajun, Zhang, Wei, Wang, Zhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746405/ https://www.ncbi.nlm.nih.gov/pubmed/29299170 http://dx.doi.org/10.18632/oncotarget.22833 |
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