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PKM2 in carcinogenesis and oncotherapy

Tumor cell metabolism is characterized by abundant glucose consumption and aerobic glycolysis. And pyruvate kinase M2 (PKM2) plays a decisive role in glycolysis, significantly contributing to the Warburg effect, tumor growth, angiogenesis, cell division, metastasis and apoptosis. To date, researcher...

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Detalles Bibliográficos
Autores principales:	He, Xia, Du, Suya, Lei, Tiantian, Li, Xiang, Liu, Yilong, Wang, Hailian, Tong, Rongsheng, Wang, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746412/ https://www.ncbi.nlm.nih.gov/pubmed/29299177 http://dx.doi.org/10.18632/oncotarget.22529

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