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The role of astrocytes in amyloid production and Alzheimer's disease
Alzheimer's disease (AD) is marked by the presence of extracellular amyloid beta (Aβ) plaques, intracellular neurofibrillary tangles (NFTs) and gliosis, activated glial cells, in the brain. It is thought that Aβ plaques trigger NFT formation, neuronal cell death, neuroinflammation and gliosis a...
Autores principales: | Frost, Georgia R., Li, Yue-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746550/ https://www.ncbi.nlm.nih.gov/pubmed/29237809 http://dx.doi.org/10.1098/rsob.170228 |
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