Endoscopic Resection for Early-Stage Esophageal Cancer, Are We There for Squamous As Well?

Superficial esophageal squamous cell cancer (SESCC) is often managed with esophagectomy with or without chemoradiotherapy. Esophagectomy has a significant complication rate and is not an option for many patients. In the current issue, a retrospective single center study evaluated 66 patients with SE...

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Autores principales: Shah, Rushikesh, Willingham, Field F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746602/
https://www.ncbi.nlm.nih.gov/pubmed/29240732
http://dx.doi.org/10.1038/ctg.2017.56
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author Shah, Rushikesh
Willingham, Field F
author_facet Shah, Rushikesh
Willingham, Field F
author_sort Shah, Rushikesh
collection PubMed
description Superficial esophageal squamous cell cancer (SESCC) is often managed with esophagectomy with or without chemoradiotherapy. Esophagectomy has a significant complication rate and is not an option for many patients. In the current issue, a retrospective single center study evaluated 66 patients with SESCC. With endoscopic resection followed by adjuvant chemoradiotherapy, the reported 1-, 3- and 5-year overall survival rates were 98%, 87% and 75% respectively, comparable to survival rates after esophagectomy or definitive chemoradiotherapy. This study suggests a key role for endoscopic management in SESCC, and provides important data on the combination of endoscopic management plus adjuvant chemoradiation.
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spelling pubmed-57466022018-01-11 Endoscopic Resection for Early-Stage Esophageal Cancer, Are We There for Squamous As Well? Shah, Rushikesh Willingham, Field F Clin Transl Gastroenterol Editorial Superficial esophageal squamous cell cancer (SESCC) is often managed with esophagectomy with or without chemoradiotherapy. Esophagectomy has a significant complication rate and is not an option for many patients. In the current issue, a retrospective single center study evaluated 66 patients with SESCC. With endoscopic resection followed by adjuvant chemoradiotherapy, the reported 1-, 3- and 5-year overall survival rates were 98%, 87% and 75% respectively, comparable to survival rates after esophagectomy or definitive chemoradiotherapy. This study suggests a key role for endoscopic management in SESCC, and provides important data on the combination of endoscopic management plus adjuvant chemoradiation. Nature Publishing Group 2017-12 2017-12-14 /pmc/articles/PMC5746602/ /pubmed/29240732 http://dx.doi.org/10.1038/ctg.2017.56 Text en Copyright © 2017 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ Clinical and Translational Gastroenterology is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Editorial
Shah, Rushikesh
Willingham, Field F
Endoscopic Resection for Early-Stage Esophageal Cancer, Are We There for Squamous As Well?
title Endoscopic Resection for Early-Stage Esophageal Cancer, Are We There for Squamous As Well?
title_full Endoscopic Resection for Early-Stage Esophageal Cancer, Are We There for Squamous As Well?
title_fullStr Endoscopic Resection for Early-Stage Esophageal Cancer, Are We There for Squamous As Well?
title_full_unstemmed Endoscopic Resection for Early-Stage Esophageal Cancer, Are We There for Squamous As Well?
title_short Endoscopic Resection for Early-Stage Esophageal Cancer, Are We There for Squamous As Well?
title_sort endoscopic resection for early-stage esophageal cancer, are we there for squamous as well?
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746602/
https://www.ncbi.nlm.nih.gov/pubmed/29240732
http://dx.doi.org/10.1038/ctg.2017.56
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