Biosensor Technology Reveals the Disruption of the Endothelial Barrier Function and the Subsequent Death of Blood Brain Barrier Endothelial Cells to Sodium Azide and Its Gaseous Products

Herein we demonstrate the sensitive nature of human blood-brain barrier (BBB) endothelial cells to sodium azide and its gaseous product. Sodium azide is known to be acutely cytotoxic at low millimolar concentrations, hence its use as a biological preservative (e.g., in antibodies). Loss of barrier i...

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Detalles Bibliográficos
Autores principales: Kho, Dan T., Johnson, Rebecca H., O’Carroll, Simon J., Angel, Catherine E., Graham, E. Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746764/
https://www.ncbi.nlm.nih.gov/pubmed/28934106
http://dx.doi.org/10.3390/bios7040041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746764/
https://www.ncbi.nlm.nih.gov/pubmed/28934106
http://dx.doi.org/10.3390/bios7040041

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