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Spontaneous Charge Generation in Flowing Albumin Solutions at 35 °C and 38 °C

The time dependence of a charge accumulation in a 10(−15) M albumin solution, flowing through a measuring cell of an analytical flow system injector, had a nonlinear character under certain conditions, within a human physiological temperature range. Sharp charge increases depended on albumin concent...

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Detalles Bibliográficos
Autores principales: Ivanov, Yuri D., Kozlov, Andrey F., Galiullin, Rafael A., Kolesanova, Ekaterina F., Pleshakova, Tatyana O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746783/
https://www.ncbi.nlm.nih.gov/pubmed/29232911
http://dx.doi.org/10.3390/bios7040060
Descripción
Sumario:The time dependence of a charge accumulation in a 10(−15) M albumin solution, flowing through a measuring cell of an analytical flow system injector, had a nonlinear character under certain conditions, within a human physiological temperature range. Sharp charge increases depended on albumin concentration. This effect must be taken into consideration when generating models that describe electrokinetic phenomena in flowing protein solutions and when developing analytical flow systems for the registration of biomolecules in low concentration ranges.