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Synthesis of Diverse 11- and 12-Membered Macrolactones from a Common Linear Substrate Using a Single Biocatalyst
[Image: see text] The diversification of late stage synthetic intermediates provides significant advantages in efficiency in comparison to conventional linear approaches. Despite these advantages, accessing varying ring scaffolds and functional group patterns from a common intermediate poses conside...
Autores principales: | Gilbert, Michael M., DeMars, Matthew D., Yang, Song, Grandner, Jessica M., Wang, Shoulei, Wang, Hengbin, Narayan, Alison R. H., Sherman, David H., Houk, K. N., Montgomery, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746868/ https://www.ncbi.nlm.nih.gov/pubmed/29296671 http://dx.doi.org/10.1021/acscentsci.7b00450 |
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