Toxicity Assessment of Carbon Nanomaterials in Zebrafish during Development

Carbon nanomaterials (CNMs) are increasingly employed in nanomedicine as carriers for intracellular transport of drugs, imaging probes, and therapeutics agents, thanks to their unique optical and physicochemical properties. However, a better understanding about the effects of CNMs on a vertebrate mo...

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Autores principales: d’Amora, Marta, Camisasca, Adalberto, Lettieri, Stefania, Giordani, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746904/
https://www.ncbi.nlm.nih.gov/pubmed/29186817
http://dx.doi.org/10.3390/nano7120414
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author d’Amora, Marta
Camisasca, Adalberto
Lettieri, Stefania
Giordani, Silvia
author_facet d’Amora, Marta
Camisasca, Adalberto
Lettieri, Stefania
Giordani, Silvia
author_sort d’Amora, Marta
collection PubMed
description Carbon nanomaterials (CNMs) are increasingly employed in nanomedicine as carriers for intracellular transport of drugs, imaging probes, and therapeutics agents, thanks to their unique optical and physicochemical properties. However, a better understanding about the effects of CNMs on a vertebrate model at the whole animal level is required. In this study, we compare the toxicity of oxidized carbon nano-onions (oxi-CNOs), oxidized carbon nano-horns (oxi-CNHs) and graphene oxide (GO) in zebrafish (Danio rerio). We evaluate the possible effects of these nanomaterials on zebrafish development by assessing different end-points and exposure periods.
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spelling pubmed-57469042018-01-03 Toxicity Assessment of Carbon Nanomaterials in Zebrafish during Development d’Amora, Marta Camisasca, Adalberto Lettieri, Stefania Giordani, Silvia Nanomaterials (Basel) Article Carbon nanomaterials (CNMs) are increasingly employed in nanomedicine as carriers for intracellular transport of drugs, imaging probes, and therapeutics agents, thanks to their unique optical and physicochemical properties. However, a better understanding about the effects of CNMs on a vertebrate model at the whole animal level is required. In this study, we compare the toxicity of oxidized carbon nano-onions (oxi-CNOs), oxidized carbon nano-horns (oxi-CNHs) and graphene oxide (GO) in zebrafish (Danio rerio). We evaluate the possible effects of these nanomaterials on zebrafish development by assessing different end-points and exposure periods. MDPI 2017-11-25 /pmc/articles/PMC5746904/ /pubmed/29186817 http://dx.doi.org/10.3390/nano7120414 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
d’Amora, Marta
Camisasca, Adalberto
Lettieri, Stefania
Giordani, Silvia
Toxicity Assessment of Carbon Nanomaterials in Zebrafish during Development
title Toxicity Assessment of Carbon Nanomaterials in Zebrafish during Development
title_full Toxicity Assessment of Carbon Nanomaterials in Zebrafish during Development
title_fullStr Toxicity Assessment of Carbon Nanomaterials in Zebrafish during Development
title_full_unstemmed Toxicity Assessment of Carbon Nanomaterials in Zebrafish during Development
title_short Toxicity Assessment of Carbon Nanomaterials in Zebrafish during Development
title_sort toxicity assessment of carbon nanomaterials in zebrafish during development
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746904/
https://www.ncbi.nlm.nih.gov/pubmed/29186817
http://dx.doi.org/10.3390/nano7120414
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AT lettieristefania toxicityassessmentofcarbonnanomaterialsinzebrafishduringdevelopment
AT giordanisilvia toxicityassessmentofcarbonnanomaterialsinzebrafishduringdevelopment

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