Involvements of p38 MAPK and oxidative stress in the ozone-induced enhancement of AHR and pulmonary inflammation in an allergic asthma model

BACKGROUND: Exposure to ambient ozone (O(3)) increases the susceptivity to allergens and triggers exacerbations in patients with asthma. However, the detailed mechanisms of action for O(3) to trigger asthma exacerbations are still unclear. METHODS: An ovalbumin (OVA)-established asthmatic mouse mode...

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Detalles Bibliográficos
Autores principales: Bao, Aihua, Yang, Hong, Ji, Jie, Chen, Yuqin, Bao, Wuping, Li, Feng, Zhang, Min, Zhou, Xin, Li, Qiang, Ben, Suqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747109/
https://www.ncbi.nlm.nih.gov/pubmed/29284473
http://dx.doi.org/10.1186/s12931-017-0697-4

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