Cargando…

Baicalin Suppresses Hypoxia-Reoxygenation-Induced Arterial Endothelial Cell Apoptosis via Suppressing PKCδ/p53 Signaling

BACKGROUND: This study was aimed to investigate the protective role of baicalin on vascular endothelium exposed to ischemia reperfusion injury and the involved molecular mechanisms. MATERIAL/METHODS: Cultured human arterial endothelial cells (HAECs) were exposed to hypoxia/deoxygenation (H/R). Cells...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shou, Xiaoling, Wang, Bozhong, Zhou, Rongfang, Wang, Lei, Ren, Aihua, Xin, Shangping, Zhu, Liyue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2017
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747146/ https://www.ncbi.nlm.nih.gov/pubmed/29272263 http://dx.doi.org/10.12659/MSM.907989

Ejemplares similares

Emodin, A Chinese Herbal Medicine, Inhibits Reoxygenation-Induced Injury in Cultured Human Aortic Endothelial Cells by Regulating the Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ) and Endothelial Nitric Oxide Synthase (eNOS) Signaling Pathway
por: Shou, Xiaoling, et al.
Publicado: (2018)

Baicalin Inhibits Human Cervical Cancer Cells by Suppressing Protein Kinase C/Signal Transducer and Activator of Transcription (PKC/STAT3) Signaling Pathway
por: Wang, Qianqian, et al.
Publicado: (2018)

Thrombin Aggravates Hypoxia/Reoxygenation Injury of Cardiomyocytes by Activating an Autophagy Pathway-Mediated by SIRT1
por: Wang, Xiaoning, et al.
Publicado: (2021)

Baicalin Regulates Proliferation, Apoptosis, Migration, and Invasion in Mesothelioma
por: Xu, Wen-Fei, et al.
Publicado: (2019)

Curcumin Suppresses Apoptosis and Inflammation in Hypoxia/Reperfusion-Exposed Neurons via Wnt Signaling Pathway
por: Zhou, Jiaxing, et al.
Publicado: (2020)

Thyroid Hormone Metabolite 3-Iodothyronamine (T1AM) Alleviates Hypoxia/Reoxygenation-Induced Cardiac Myocyte Apoptosis via Akt/FoxO1 Pathway
por: Zhou, Haiyan, et al.
Publicado: (2020)

Downregulation of Inhibition of Apoptosis-Stimulating Protein of p53 (iASPP) Suppresses Cisplatin-Resistant Gastric Carcinoma In Vitro
por: Yu, Jianyong, et al.
Publicado: (2017)

Metformin Suppresses Proliferation and Viability of Rat Pheochromocytoma Cells
por: Li, Min, et al.
Publicado: (2017)

MiR-206 Suppresses the Progression of Coronary Artery Disease by Modulating Vascular Endothelial Growth Factor (VEGF) Expression
por: Wang, Maojing, et al.
Publicado: (2016)

A Regulatory Axis of circ_0008193/miR-1180-3p/TRIM62 Suppresses Proliferation, Migration, Invasion, and Warburg Effect in Lung Adenocarcinoma Cells Under Hypoxia
por: Chen, Minbiao, et al.
Publicado: (2020)

Peroxiredoxin 1 (PRDX1) Suppresses Progressions and Metastasis of Osteosarcoma and Fibrosarcoma of Bone
por: Wang, Yongxiang, et al.
Publicado: (2018)

Cytoprotective Effects and Mechanisms of Δ-17 Fatty Acid Desaturase in Injured Human Umbilical Vein Endothelial Cells (HUVECs)
por: Zhou, Haoyu, et al.
Publicado: (2017)

Emodin Impairs Radioresistance of Human Osteosarcoma Cells by Suppressing Sonic Hedgehog Signaling
por: Qu, Wei, et al.
Publicado: (2017)

Resveratrol Induces Apoptosis in Murine Prostate Cancer Cells via Hypoxia-Inducible Factor 1-alpha (HIF-1α)/Reactive Oxygen Species (ROS)/P53 Signaling
por: Wang, Delong, et al.
Publicado: (2018)

Cryptochrome 2 (CRY2) Suppresses Proliferation and Migration and Regulates Clock Gene Network in Osteosarcoma Cells
por: Yu, Yueming, et al.
Publicado: (2018)

Gambogic Acid Induces Apoptosis of Non-Small Cell Lung Cancer (NSCLC) Cells by Suppressing Notch Signaling
por: Zhu, Minghua, et al.
Publicado: (2018)

IC-2 Suppresses Proliferation and Induces Apoptosis of Bladder Cancer Cells via the Wnt/β-Catenin Pathway
por: Wu, Lingfeng, et al.
Publicado: (2018)

MicroRNA-449b-5p Suppresses Proliferation, Migration, and Invasion of Osteosarcoma by Targeting c-Met
por: Li, Qian, et al.
Publicado: (2019)

Sufentanil Preconditioning Protects Against Hepatic Ischemia-Reperfusion Injury by Suppressing Inflammation
por: Lian, Yan-hong, et al.
Publicado: (2019)

Peptidoglycan Suppresses Phagocytic Activities and Apoptosis of Macrophages in Colonic Mucosa Tissues of Crohn’s Disease Patients and In Vitro
por: Jing, Yang, et al.
Publicado: (2018)

Suppression of Apoptosis in Human Umbilical Vein Endothelial Cells (HUVECs) by Klotho Protein is Associated with Reduced Endoplasmic Reticulum Oxidative Stress and Activation of the PI3K/AKT Pathway
por: Cui, Wei, et al.
Publicado: (2018)

Adenovirus-Mediated siRNA Targeting CXCR2 Attenuates Titanium Particle-Induced Osteolysis by Suppressing Osteoclast Formation
por: Wang, Chen, et al.
Publicado: (2016)

Cervical Cancer Cell Growth, Drug Resistance, and Epithelial-Mesenchymal Transition Are Suppressed by γ-Secretase Inhibitor RO4929097
por: Wang, Lu, et al.
Publicado: (2018)

Basic Fibroblast Growth Factor Reduces Permeability and Apoptosis of Human Brain Microvascular Endothelial Cells in Response to Oxygen and Glucose Deprivation Followed by Reoxygenation via the Fibroblast Growth Factor Receptor 1 (FGFR1)/ERK Pathway
por: Chen, Peng, et al.
Publicado: (2019)

Baicalin Inhibits Cell Proliferation and Inflammatory Cytokines Induced by Tumor Necrosis Factor α (TNF-α) in Human Immortalized Keratinocytes (HaCaT) Human Keratinocytes by Inhibiting the STAT3/Nuclear Factor kappa B (NF-κB) Signaling Pathway
por: Wu, Xianwei, et al.
Publicado: (2020)

Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro
por: Wang, Chunhua, et al.
Publicado: (2018)

Distinct Anti-Fibrotic Effects of Exosomes Derived from Endothelial Colony-Forming Cells Cultured Under Normoxia and Hypoxia
por: Liu, WenHao, et al.
Publicado: (2018)

Baicalin, a Chinese Herbal Medicine, Inhibits the Proliferation and Migration of Human Non-Small Cell Lung Carcinoma (NSCLC) Cells, A549 and H1299, by Activating the SIRT1/AMPK Signaling Pathway
por: You, Jiawen, et al.
Publicado: (2018)

Aberrant Expression of microRNA-9 Contributes to Development of Intracranial Aneurysm by Suppressing Proliferation and Reducing Contractility of Smooth Muscle Cells
por: Luo, Jing, et al.
Publicado: (2016)

Caveolin-1 Inhibits Proliferation, Migration, and Invasion of Human Colorectal Cancer Cells by Suppressing Phosphorylation of Epidermal Growth Factor Receptor
por: Yang, Juanli, et al.
Publicado: (2018)

miR-483-5p Targets MKNK1 to Suppress Wilms’ Tumor Cell Proliferation and Apoptosis In Vitro and In Vivo
por: Liu, Kai, et al.
Publicado: (2019)

TESTIN suppresses tumor growth and invasion via manipulating cell cycle progression in endometrial carcinoma
por: Gu, Zhenpeng, et al.
Publicado: (2014)

Prostacyclin Suppresses Twist Expression in the Presence of Indomethacin in Bone Marrow-Derived Mesenchymal Stromal Cells
por: Kemper, Oliver, et al.
Publicado: (2014)

Steroid Receptor Coactivator-Interacting Protein (SIP) Suppresses Myocardial Injury Caused by Acute Pancreatitis
por: Chen, Xin, et al.
Publicado: (2018)

Butyrophilin-Like 9 (BTNL9) Suppresses Invasion and Correlates with Favorable Prognosis of Uveal Melanoma
por: Jiang, Zhongming, et al.
Publicado: (2019)

miR-18a Inhibitor Suppresses Leukemia Cell Proliferation by Upregulation of PTEN Expression
por: Zhang, Liping, et al.
Publicado: (2020)

Sonidegib, a Smoothened Inhibitor, Promotes Apoptosis and Suppresses Proliferation of Natural Killer/T-Cell Lymphoma
por: Liu, Shengquan, et al.
Publicado: (2019)

Upregulation of Nuclear Factor IA Suppresses Oxidized Low-Density Lipoprotein-Induced Endoplasmic Reticulum Stress and Apoptosis in Human Umbilical Vein Endothelial Cells
por: Zhou, Zhenyu, et al.
Publicado: (2019)

Zinc Finger E-Box Binding Protein 2 (ZEB2) Suppress Apoptosis of Vascular Endothelial Cells Induced by High Glucose Through Mitogen-Activated Protein Kinases (MAPK) Pathway Activation
por: Wang, Lin-Jun, et al.
Publicado: (2017)

Long Noncoding RNA DANCR Suppressed Lipopolysaccharide-Induced Septic Acute Kidney Injury by Regulating miR-214 in HK-2 Cells
por: Zhao, Huajie, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_e20k0g2jf2jl180j8e2jdgp6cr