Lack of SOCS3 increases LPS-induced murine acute lung injury through modulation of Ly6C(+) macrophages

BACKGROUND: SOCS3 (suppressor of cytokine signaling 3) is a negative regulator of JAK/STAT3 signaling pathway and participates in the regulation of lung inflammation in a mouse model with acute lung injury (ALI). However, it is not well understood how SOCS3 regulates lung inflammation in the ALI mou...

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Detalles Bibliográficos
Autores principales: Jiang, Zhilong, Chen, Zhihong, Li, Liyang, Zhou, Wenjun, Zhu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747159/
https://www.ncbi.nlm.nih.gov/pubmed/29284516
http://dx.doi.org/10.1186/s12931-017-0707-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747159/
https://www.ncbi.nlm.nih.gov/pubmed/29284516
http://dx.doi.org/10.1186/s12931-017-0707-6

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