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Lack of SOCS3 increases LPS-induced murine acute lung injury through modulation of Ly6C(+) macrophages

BACKGROUND: SOCS3 (suppressor of cytokine signaling 3) is a negative regulator of JAK/STAT3 signaling pathway and participates in the regulation of lung inflammation in a mouse model with acute lung injury (ALI). However, it is not well understood how SOCS3 regulates lung inflammation in the ALI mou...

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Detalles Bibliográficos
Autores principales:	Jiang, Zhilong, Chen, Zhihong, Li, Liyang, Zhou, Wenjun, Zhu, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747159/ https://www.ncbi.nlm.nih.gov/pubmed/29284516 http://dx.doi.org/10.1186/s12931-017-0707-6

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