Postnatal lethality and chondrodysplasia in mice lacking both chondroitin sulfate N-acetylgalactosaminyltransferase-1 and -2

Chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) chain. In cartilage, CS plays important roles as the main component of the extracellular matrix (ECM), existing as side chains of the major cartilage proteoglycan, aggrecan. Six glycosyltransferases are known to coordinately synthesize t...

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Detalles Bibliográficos
Autores principales: Shimbo, Miki, Suzuki, Riku, Fuseya, Sayaka, Sato, Takashi, Kiyohara, Katsue, Hagiwara, Kozue, Okada, Risa, Wakui, Hiromasa, Tsunakawa, Yuki, Watanabe, Hideto, Kimata, Koji, Narimatsu, Hisashi, Kudo, Takashi, Takahashi, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747463/
https://www.ncbi.nlm.nih.gov/pubmed/29287114
http://dx.doi.org/10.1371/journal.pone.0190333

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