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Mitochondrial DNA depletion by ethidium bromide decreases neuronal mitochondrial creatine kinase: Implications for striatal energy metabolism

Mitochondrial DNA (mtDNA), the discrete genome which encodes subunits of the mitochondrial respiratory chain, is present at highly variable copy numbers across cell types. Though severe mtDNA depletion dramatically reduces mitochondrial function, the impact of tissue-specific mtDNA reduction remains...

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Detalles Bibliográficos
Autores principales:	Warren, Emily Booth, Aicher, Aidan Edward, Fessel, Joshua Patrick, Konradi, Christine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747477/ https://www.ncbi.nlm.nih.gov/pubmed/29287112 http://dx.doi.org/10.1371/journal.pone.0190456

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