Cargando…

Calcium-mediated shaping of naive CD4 T-cell phenotype and function

Continuous contact with self-major histocompatibility complex ligands is essential for the survival of naive CD4 T cells. We have previously shown that the resulting tonic TCR signaling also influences their fate upon activation by increasing their ability to differentiate into induced/peripheral re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guichard, Vincent, Bonilla, Nelly, Durand, Aurélie, Audemard-Verger, Alexandra, Guilbert, Thomas, Martin, Bruno, Lucas, Bruno, Auffray, Cédric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747519/ https://www.ncbi.nlm.nih.gov/pubmed/29239722 http://dx.doi.org/10.7554/eLife.27215

Ejemplares similares

Profiling the lymphoid-resident T cell pool reveals modulation by age and microbiota
por: Durand, Aurélie, et al.
Publicado: (2018)

Sepsis impedes EAE disease development and diminishes autoantigen-specific naive CD4 T cells
por: Jensen, Isaac J, et al.
Publicado: (2020)

CD4(+) T-cell cooperation promoted pathogenic function of activated naïve B cells of patients with SLE
por: Wangriatisak, Kittikorn, et al.
Publicado: (2022)

Preexisting memory CD4 T cells in naïve individuals confer robust immunity upon hepatitis B vaccination
por: Elias, George, et al.
Publicado: (2022)

Mitochondrial superoxide disrupts the metabolic and epigenetic landscape of CD4(+) and CD8(+) T-lymphocytes
por: Moshfegh, C.M., et al.
Publicado: (2019)

Sepsis leads to lasting changes in phenotype and function of memory CD8 T cells
por: Jensen, Isaac J, et al.
Publicado: (2021)

Mapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum
por: Milne, Kathryn, et al.
Publicado: (2021)

Functional and phenotypical analysis of IL‐6‐secreting CD4(+) T cells in human adipose tissue
por: de Jong, Anja J., et al.
Publicado: (2018)

Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells
por: Jimeno, Rebeca, et al.
Publicado: (2019)

Correction: Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells
por: Jimeno, Rebeca, et al.
Publicado: (2020)

ARPC5 isoforms and their regulation by calcium-calmodulin-N-WASP drive distinct Arp2/3-dependent actin remodeling events in CD4 T cells
por: Sadhu, Lopamudra, et al.
Publicado: (2023)

HDAC3 restrains CD8-lineage genes to maintain a bi-potential state in CD4(+)CD8(+) thymocytes for CD4-lineage commitment
por: Philips, Rachael Laura, et al.
Publicado: (2019)

Empty conformers of HLA-B preferentially bind CD8 and regulate CD8(+) T cell function
por: Geng, Jie, et al.
Publicado: (2018)

CD47 cross-dressing by extracellular vesicles expressing CD47 inhibits phagocytosis without transmitting cell death signals
por: Li, Yang, et al.
Publicado: (2022)

The regional distribution of resident immune cells shapes distinct immunological environments along the murine epididymis
por: Pleuger, Christiane, et al.
Publicado: (2022)

Intravital quantification reveals dynamic calcium concentration changes across B cell differentiation stages
por: Ulbricht, Carolin, et al.
Publicado: (2021)

SARS-CoV-2 uses CD4 to infect T helper lymphocytes
por: Brunetti, Natalia S, et al.
Publicado: (2023)

Chronic inflammatory demyelinating polyradiculoneuropathy: from pathology to phenotype
por: Mathey, Emily K, et al.
Publicado: (2015)

Conserved biophysical compatibility among the highly variable germline-encoded regions shapes TCR-MHC interactions
por: Boughter, Christopher T, et al.
Publicado: (2023)

Selective loss of CD107a TIGIT+ memory HIV-1-specific CD8+ T cells in PLWH over a decade of ART
por: Blanch-Lombarte, Oscar, et al.
Publicado: (2023)

Correlation between leukocyte phenotypes and prognosis of amyotrophic lateral sclerosis
por: Cui, Can, et al.
Publicado: (2022)

A case of emphysematous pyelonephritis caused by the hypermucoviscosity phenotype of Klebsiellapneumoniae
por: Kawaguchi, Yoshihiro, et al.
Publicado: (2022)

Expansion of CD10(neg) neutrophils and CD14(+)HLA-DR(neg/low) monocytes driving proinflammatory responses in patients with acute myocardial infarction
por: Fraccarollo, Daniela, et al.
Publicado: (2021)

SARS-CoV-2-specific CD4(+) and CD8(+) T cell responses can originate from cross-reactive CMV-specific T cells
por: Pothast, Cilia R, et al.
Publicado: (2022)

TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia
por: Jairaman, Amit, et al.
Publicado: (2022)

Structural variability and concerted motions of the T cell receptor – CD3 complex
por: Pandey, Prithvi R, et al.
Publicado: (2021)

B cell receptor-induced IL-10 production from neonatal mouse CD19(+)CD43(-) cells depends on STAT5-mediated IL-6 secretion
por: Sakai, Jiro, et al.
Publicado: (2023)

LGI1, CASPR2 and related antibodies: a molecular evolution of the phenotypes
por: Binks, Sophie N M, et al.
Publicado: (2018)

Loss of GTPase activating protein neurofibromin stimulates paracrine cell communication via macropinocytosis
por: Ghoshal, Pushpankur, et al.
Publicado: (2019)

Role of Inflammation in Coronary Epicardial and Microvascular Dysfunction
por: Godo, Shigeo, et al.
Publicado: (2021)

Anti-inflammatory Treatment and Cardiovascular Outcomes: Results of Clinical Trials
por: Lorenzatti, Alberto J
Publicado: (2021)

Atherosclerotic Cardiovascular Disease in Rheumatoid Arthritis: Impact of Inflammation and Antirheumatic Treatment
por: Kerola, Anne Mirjam, et al.
Publicado: (2021)

The Role of C-reactive Protein in Patient Risk Stratification and Treatment
por: Arroyo-Espliguero, Ramón, et al.
Publicado: (2021)

Inflammation and Cardiovascular Disease: The Future
por: Arnold, Natalie, et al.
Publicado: (2021)

Small bowel stomas are associated with higher risk of circulating food-specific-IgG than patients with organic gastrointestinal conditions and colostomies
por: Carson, Walker K, et al.
Publicado: (2022)

Functional proteomic atlas of HIV infection in primary human CD4+ T cells
por: Naamati, Adi, et al.
Publicado: (2019)

Complement and CD4(+) T cells drive context-specific corneal sensory neuropathy
por: Royer, Derek J, et al.
Publicado: (2019)

CD8(+) T cell self-tolerance permits responsiveness but limits tissue damage
por: Truckenbrod, Emily N, et al.
Publicado: (2021)

Biallelic mutations in calcium release activated channel regulator 2A (CRACR2A) cause a primary immunodeficiency disorder
por: Wu, Beibei, et al.
Publicado: (2021)

Differential impact of self and environmental antigens on the ontogeny and maintenance of CD4(+) T cell memory
por: Hogan, Thea, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_esru6qgqdg86p0i76vm2660se7