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Network analysis identifies chromosome intermingling regions as regulatory hotspots for transcription

The 3D structure of the genome plays a key role in regulatory control of the cell. Experimental methods such as high-throughput chromosome conformation capture (Hi-C) have been developed to probe the 3D structure of the genome. However, it remains a challenge to deduce from these data chromosome reg...

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Detalles Bibliográficos
Autores principales: Belyaeva, Anastasiya, Venkatachalapathy, Saradha, Nagarajan, Mallika, Shivashankar, G. V., Uhler, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748172/
https://www.ncbi.nlm.nih.gov/pubmed/29229825
http://dx.doi.org/10.1073/pnas.1708028115