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Molecular mechanism for the subversion of the retromer coat by the Legionella effector RidL

Microbial pathogens employ sophisticated virulence strategies to cause infections in humans. The intracellular pathogen Legionella pneumophila encodes RidL to hijack the host scaffold protein VPS29, a component of retromer and retriever complexes critical for endosomal cargo recycling. Here, we dete...

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Detalles Bibliográficos
Autores principales: Romano-Moreno, Miguel, Rojas, Adriana L., Williamson, Chad D., Gershlick, David C., Lucas, María, Isupov, Michail N., Bonifacino, Juan S., Machner, Matthias P., Hierro, Aitor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748213/
https://www.ncbi.nlm.nih.gov/pubmed/29229824
http://dx.doi.org/10.1073/pnas.1715361115