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Molecular mechanism for the subversion of the retromer coat by the Legionella effector RidL
Microbial pathogens employ sophisticated virulence strategies to cause infections in humans. The intracellular pathogen Legionella pneumophila encodes RidL to hijack the host scaffold protein VPS29, a component of retromer and retriever complexes critical for endosomal cargo recycling. Here, we dete...
Autores principales: | Romano-Moreno, Miguel, Rojas, Adriana L., Williamson, Chad D., Gershlick, David C., Lucas, María, Isupov, Michail N., Bonifacino, Juan S., Machner, Matthias P., Hierro, Aitor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748213/ https://www.ncbi.nlm.nih.gov/pubmed/29229824 http://dx.doi.org/10.1073/pnas.1715361115 |
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