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A genomic perspective on HLA evolution

Several decades of research have convincingly shown that classical human leukocyte antigen (HLA) loci bear signatures of natural selection. Despite this conclusion, many questions remain regarding the type of selective regime acting on these loci, the time frame at which selection acts, and the func...

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Detalles Bibliográficos
Autores principales: Meyer, Diogo, C. Aguiar, Vitor R., Bitarello, Bárbara D., C. Brandt, Débora Y., Nunes, Kelly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748415/
https://www.ncbi.nlm.nih.gov/pubmed/28687858
http://dx.doi.org/10.1007/s00251-017-1017-3

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