The 5-HT(2C) receptor agonist meta-chlorophenylpiperazine (mCPP) reduces palatable food consumption and BOLD fMRI responses to food images in healthy female volunteers

RATIONALE: Brain 5-HT(2C) receptors form part of a neural network that controls eating behaviour. 5-HT(2C) receptor agonists decrease food intake by activating proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus, but recent research in rodents has suggested that 5-HT(2C) re...

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Detalles Bibliográficos
Autores principales: Thomas, Jason M., Dourish, Colin T., Tomlinson, Jeremy, Hassan-Smith, Zaki, Hansen, Peter C., Higgs, Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748416/
https://www.ncbi.nlm.nih.gov/pubmed/29080906
http://dx.doi.org/10.1007/s00213-017-4764-9

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