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Emerging functions of the EGFR in cancer

The physiological function of the epidermal growth factor receptor (EGFR) is to regulate epithelial tissue development and homeostasis. In pathological settings, mostly in lung and breast cancer and in glioblastoma, the EGFR is a driver of tumorigenesis. Inappropriate activation of the EGFR in cance...

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Detalles Bibliográficos
Autores principales: Sigismund, Sara, Avanzato, Daniele, Lanzetti, Letizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748484/
https://www.ncbi.nlm.nih.gov/pubmed/29124875
http://dx.doi.org/10.1002/1878-0261.12155

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