Cargando…
Emerging functions of the EGFR in cancer
The physiological function of the epidermal growth factor receptor (EGFR) is to regulate epithelial tissue development and homeostasis. In pathological settings, mostly in lung and breast cancer and in glioblastoma, the EGFR is a driver of tumorigenesis. Inappropriate activation of the EGFR in cance...
Autores principales: | Sigismund, Sara, Avanzato, Daniele, Lanzetti, Letizia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748484/ https://www.ncbi.nlm.nih.gov/pubmed/29124875 http://dx.doi.org/10.1002/1878-0261.12155 |
Ejemplares similares
-
KRAS-Driven Metabolic Rewiring Reveals Novel Actionable Targets in Cancer
por: Pupo, Emanuela, et al.
Publicado: (2019) -
Kinesin-2 Controls the Motility of RAB5 Endosomes and Their Association with the Spindle in Mitosis
por: Pupo, Emanuela, et al.
Publicado: (2018) -
Keeping EGFR signaling in check: Ubiquitin is the guardian
por: Polo, Simona, et al.
Publicado: (2014) -
Breast cancers as ecosystems: a metabolic perspective
por: Martino, Flavia, et al.
Publicado: (2023) -
Quantitative analysis reveals how EGFR activation and downregulation are coupled in normal but not in cancer cells
por: Capuani, Fabrizio, et al.
Publicado: (2015)