A Computational Workflow Translates a 58-Gene Signature to a Formalin-Fixed, Paraffin-Embedded Sample-Based Companion Diagnostic for Personalized Treatment of the BRAF-Mutation-Like Subtype of Colorectal Cancers

Colorectal cancer patients with the BRAF(p.V600E) mutation have poor prognosis in metastatic setting. Personalized treatment options and companion diagnostics are needed to better treat these patients. Previously, we developed a 58-gene signature to characterize the distinct gene expression pattern...

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Detalles Bibliográficos
Autores principales: In’t Veld, Sjors G. J. G., Duong, Kim N., Snel, Mireille, Witteveen, Anke, Beumer, Inès J., Delahaye, Leonie J. M. J., Wehkamp, Diederik, Bernards, René, Glas, Annuska M., Tian, Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748595/
https://www.ncbi.nlm.nih.gov/pubmed/29479053
http://dx.doi.org/10.3390/ht6040016

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