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Variation in CYP2A6 Activity and Personalized Medicine

The cytochrome P450 2A6 (CYP2A6) enzyme metabolizes several clinically relevant substrates, including nicotine—the primary psychoactive component in cigarette smoke. The gene that encodes the CYP2A6 enzyme is highly polymorphic, resulting in extensive interindividual variation in CYP2A6 enzyme activ...

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Detalles Bibliográficos
Autores principales:	Tanner, Julie-Anne, Tyndale, Rachel F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748630/ https://www.ncbi.nlm.nih.gov/pubmed/29194389 http://dx.doi.org/10.3390/jpm7040018

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