Epigenetic Basis of Cellular Senescence and Its Implications in Aging

Cellular senescence is a tumor suppressive response that has become recognized as a major contributor of tissue aging. Senescent cells undergo a stable proliferative arrest that protects against neoplastic transformation, but acquire a secretory phenotype that has long-term deleterious effects. Stud...

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Detalles Bibliográficos
Autores principales: Nacarelli, Timothy, Liu, Pingyu, Zhang, Rugang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748661/
https://www.ncbi.nlm.nih.gov/pubmed/29186801
http://dx.doi.org/10.3390/genes8120343

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