Cargando…
Cognitive and Mood Effects of a Nutrient Enriched Breakfast Bar in Healthy Adults: A Randomised, Double-Blind, Placebo-Controlled, Parallel Groups Study
Objectives: Few previous studies have assessed the effects of concomitant administration of multiple potentially psychoactive nutrients. Methods: 95 healthy adult participants consumed either a nutrient enriched breakfast bar (containing α-Linolenic acid, l-tyrosine, l-theanine, vitamins, minerals a...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748782/ https://www.ncbi.nlm.nih.gov/pubmed/29215606 http://dx.doi.org/10.3390/nu9121332 |
_version_ | 1783289471758761984 |
---|---|
author | Kennedy, David O. Wightman, Emma L. Forster, Joanne Khan, Julie Haskell-Ramsay, Crystal F. Jackson, Philippa A. |
author_facet | Kennedy, David O. Wightman, Emma L. Forster, Joanne Khan, Julie Haskell-Ramsay, Crystal F. Jackson, Philippa A. |
author_sort | Kennedy, David O. |
collection | PubMed |
description | Objectives: Few previous studies have assessed the effects of concomitant administration of multiple potentially psychoactive nutrients. Methods: 95 healthy adult participants consumed either a nutrient enriched breakfast bar (containing α-Linolenic acid, l-tyrosine, l-theanine, vitamins, minerals and 21.5 mg of caffeine) or an isocaloric, macronutrient matched control bar for 56 days. Cognitive function and mood were assessed pre-dose and at 40- and 160-min post-dose on the 1st and 56th day of the intervention period. Results: The results demonstrated acute effects of treatment across post-dose assessments on both assessment days in terms of alertness, and on tasks assessing attention, working and episodic memory and executive function, including cognitively demanding Serial subtraction and Rapid Visual Information Processing tasks. There were no evident chronic effects independent of the breakfast bars’ acute effects. Discussion: These results demonstrate that a nutrient enriched breakfast bar with low caffeine content can exert striking beneficial effects on acute cognitive function and alertness. |
format | Online Article Text |
id | pubmed-5748782 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-57487822018-01-07 Cognitive and Mood Effects of a Nutrient Enriched Breakfast Bar in Healthy Adults: A Randomised, Double-Blind, Placebo-Controlled, Parallel Groups Study Kennedy, David O. Wightman, Emma L. Forster, Joanne Khan, Julie Haskell-Ramsay, Crystal F. Jackson, Philippa A. Nutrients Article Objectives: Few previous studies have assessed the effects of concomitant administration of multiple potentially psychoactive nutrients. Methods: 95 healthy adult participants consumed either a nutrient enriched breakfast bar (containing α-Linolenic acid, l-tyrosine, l-theanine, vitamins, minerals and 21.5 mg of caffeine) or an isocaloric, macronutrient matched control bar for 56 days. Cognitive function and mood were assessed pre-dose and at 40- and 160-min post-dose on the 1st and 56th day of the intervention period. Results: The results demonstrated acute effects of treatment across post-dose assessments on both assessment days in terms of alertness, and on tasks assessing attention, working and episodic memory and executive function, including cognitively demanding Serial subtraction and Rapid Visual Information Processing tasks. There were no evident chronic effects independent of the breakfast bars’ acute effects. Discussion: These results demonstrate that a nutrient enriched breakfast bar with low caffeine content can exert striking beneficial effects on acute cognitive function and alertness. MDPI 2017-12-07 /pmc/articles/PMC5748782/ /pubmed/29215606 http://dx.doi.org/10.3390/nu9121332 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Kennedy, David O. Wightman, Emma L. Forster, Joanne Khan, Julie Haskell-Ramsay, Crystal F. Jackson, Philippa A. Cognitive and Mood Effects of a Nutrient Enriched Breakfast Bar in Healthy Adults: A Randomised, Double-Blind, Placebo-Controlled, Parallel Groups Study |
title | Cognitive and Mood Effects of a Nutrient Enriched Breakfast Bar in Healthy Adults: A Randomised, Double-Blind, Placebo-Controlled, Parallel Groups Study |
title_full | Cognitive and Mood Effects of a Nutrient Enriched Breakfast Bar in Healthy Adults: A Randomised, Double-Blind, Placebo-Controlled, Parallel Groups Study |
title_fullStr | Cognitive and Mood Effects of a Nutrient Enriched Breakfast Bar in Healthy Adults: A Randomised, Double-Blind, Placebo-Controlled, Parallel Groups Study |
title_full_unstemmed | Cognitive and Mood Effects of a Nutrient Enriched Breakfast Bar in Healthy Adults: A Randomised, Double-Blind, Placebo-Controlled, Parallel Groups Study |
title_short | Cognitive and Mood Effects of a Nutrient Enriched Breakfast Bar in Healthy Adults: A Randomised, Double-Blind, Placebo-Controlled, Parallel Groups Study |
title_sort | cognitive and mood effects of a nutrient enriched breakfast bar in healthy adults: a randomised, double-blind, placebo-controlled, parallel groups study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748782/ https://www.ncbi.nlm.nih.gov/pubmed/29215606 http://dx.doi.org/10.3390/nu9121332 |
work_keys_str_mv | AT kennedydavido cognitiveandmoodeffectsofanutrientenrichedbreakfastbarinhealthyadultsarandomiseddoubleblindplacebocontrolledparallelgroupsstudy AT wightmanemmal cognitiveandmoodeffectsofanutrientenrichedbreakfastbarinhealthyadultsarandomiseddoubleblindplacebocontrolledparallelgroupsstudy AT forsterjoanne cognitiveandmoodeffectsofanutrientenrichedbreakfastbarinhealthyadultsarandomiseddoubleblindplacebocontrolledparallelgroupsstudy AT khanjulie cognitiveandmoodeffectsofanutrientenrichedbreakfastbarinhealthyadultsarandomiseddoubleblindplacebocontrolledparallelgroupsstudy AT haskellramsaycrystalf cognitiveandmoodeffectsofanutrientenrichedbreakfastbarinhealthyadultsarandomiseddoubleblindplacebocontrolledparallelgroupsstudy AT jacksonphilippaa cognitiveandmoodeffectsofanutrientenrichedbreakfastbarinhealthyadultsarandomiseddoubleblindplacebocontrolledparallelgroupsstudy |