Metabolic reprogramming of human CD8(+) memory T cells through loss of SIRT1

The expansion of CD8(+)CD28(–) T cells, a population of terminally differentiated memory T cells, is one of the most consistent immunological changes in humans during aging. CD8(+)CD28(–) T cells are highly cytotoxic, and their frequency is linked to many age-related diseases. As they do not accumul...

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Detalles Bibliográficos
Autores principales: Jeng, Mark Y., Hull, Philip A., Fei, Mingjian, Kwon, Hye-Sook, Tsou, Chia-Lin, Kasler, Herb, Ng, Che-Ping, Gordon, David E., Johnson, Jeffrey, Krogan, Nevan, Verdin, Eric, Ott, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748845/
https://www.ncbi.nlm.nih.gov/pubmed/29191913
http://dx.doi.org/10.1084/jem.20161066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748845/
https://www.ncbi.nlm.nih.gov/pubmed/29191913
http://dx.doi.org/10.1084/jem.20161066

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