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Prostate-specific membrane antigen cleavage of vitamin B9 stimulates oncogenic signaling through metabotropic glutamate receptors
Prostate-specific membrane antigen (PSMA) or folate hydrolase 1 (FOLH1) is highly expressed on prostate cancer. Its expression correlates inversely with survival and increases with tumor grade. However, the biological role of PSMA has not been explored, and its role in prostate cancer remained elusi...
Autores principales: | Kaittanis, Charalambos, Andreou, Chrysafis, Hieronymus, Haley, Mao, Ninghui, Foss, Catherine A., Eiber, Matthias, Weirich, Gregor, Panchal, Palak, Gopalan, Anuradha, Zurita, Juan, Achilefu, Samuel, Chiosis, Gabriela, Ponomarev, Vladimir, Schwaiger, Markus, Carver, Brett S., Pomper, Martin G., Grimm, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748857/ https://www.ncbi.nlm.nih.gov/pubmed/29141866 http://dx.doi.org/10.1084/jem.20171052 |
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