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Mannose receptor high, M2 dermal macrophages mediate nonhealing Leishmania major infection in a Th1 immune environment

The origin and functional specialization of dermal macrophages in cutaneous infections have been little studied. In this paper, we show that a strain of Leishmania major (L. major Seidman [LmSd]) that produces nonhealing cutaneous lesions in conventionally resistant C57BL/6 mice was more efficiently...

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Detalles Bibliográficos
Autores principales:	Lee, Sang Hun, Charmoy, Melanie, Romano, Audrey, Paun, Andrea, Chaves, Mariana M., Cope, Frederick O., Ralph, David A., Sacks, David L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748861/ https://www.ncbi.nlm.nih.gov/pubmed/29247046 http://dx.doi.org/10.1084/jem.20171389

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