PSMA brings new flavors to PI3K signaling: A role for glutamate in prostate cancer

In this issue of JEM, Kaittanis et al. (https://doi.org/10.1084/jem.20171052) report a new signaling role for prostate-specific membrane antigen (PSMA), providing a mechanistic link between two major oncogenic pathways, as well as promising therapeutic implications for the diagnosis and treatment of...

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Detalles Bibliográficos
Autores principales: Palamiuc, Lavinia, Emerling, Brooke M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
News
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748867/
https://www.ncbi.nlm.nih.gov/pubmed/29222106
http://dx.doi.org/10.1084/jem.20172050
Descripción
Sumario:In this issue of JEM, Kaittanis et al. (https://doi.org/10.1084/jem.20171052) report a new signaling role for prostate-specific membrane antigen (PSMA), providing a mechanistic link between two major oncogenic pathways, as well as promising therapeutic implications for the diagnosis and treatment of prostate cancer.

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