IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases

Primary cilia have pivotal roles as organizers of many different signaling pathways, including platelet-derived growth factor receptor α (PDGFRα) signaling, which, when aberrantly regulated, is associated with developmental disorders, tumorigenesis, and cancer. PDGFRα is up-regulated during ciliogen...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmid, Fabian Marc, Schou, Kenneth Bødtker, Vilhelm, Martin Juel, Holm, Maria Schrøder, Breslin, Loretta, Farinelli, Pietro, Larsen, Lars Allan, Andersen, Jens Skorstengaard, Pedersen, Lotte Bang, Christensen, Søren Tvorup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748969/
https://www.ncbi.nlm.nih.gov/pubmed/29237719
http://dx.doi.org/10.1083/jcb.201611050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748969/
https://www.ncbi.nlm.nih.gov/pubmed/29237719
http://dx.doi.org/10.1083/jcb.201611050

Ejemplares similares