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IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases

Primary cilia have pivotal roles as organizers of many different signaling pathways, including platelet-derived growth factor receptor α (PDGFRα) signaling, which, when aberrantly regulated, is associated with developmental disorders, tumorigenesis, and cancer. PDGFRα is up-regulated during ciliogen...

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Detalles Bibliográficos
Autores principales:	Schmid, Fabian Marc, Schou, Kenneth Bødtker, Vilhelm, Martin Juel, Holm, Maria Schrøder, Breslin, Loretta, Farinelli, Pietro, Larsen, Lars Allan, Andersen, Jens Skorstengaard, Pedersen, Lotte Bang, Christensen, Søren Tvorup
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748969/ https://www.ncbi.nlm.nih.gov/pubmed/29237719 http://dx.doi.org/10.1083/jcb.201611050

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