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Protein sequestration at the nuclear periphery as a potential regulatory mechanism in premature aging
Despite the extensive description of numerous molecular changes associated with aging, insights into the driver mechanisms of this fundamental biological process are limited. Based on observations in the premature aging syndrome Hutchinson–Gilford progeria, we explore the possibility that protein re...
Autores principales: | Serebryannyy, Leonid, Misteli, Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748986/ https://www.ncbi.nlm.nih.gov/pubmed/29051264 http://dx.doi.org/10.1083/jcb.201706061 |
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