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Aurora A activation in mitosis promoted by BuGZ
Protein phase separation or coacervation has emerged as a potential mechanism to regulate biological functions. We have shown that coacervation of a mostly unstructured protein, BuGZ, promotes assembly of spindle and its matrix. BuGZ in the spindle matrix binds and concentrates tubulin to promote mi...
Autores principales: | Huang, Yuejia, Li, Teng, Ems-McClung, Stephanie C., Walczak, Claire E., Prigent, Claude, Zhu, Xueliang, Zhang, Xuemin, Zheng, Yixian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748987/ https://www.ncbi.nlm.nih.gov/pubmed/29074706 http://dx.doi.org/10.1083/jcb.201706103 |
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