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INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division

Mitochondrial division requires division of both the inner and outer mitochondrial membranes (IMM and OMM, respectively). Interaction with endoplasmic reticulum (ER) promotes OMM division by recruitment of the dynamin Drp1, but effects on IMM division are not well characterized. We previously showed...

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Detalles Bibliográficos
Autores principales: Chakrabarti, Rajarshi, Ji, Wei-Ke, Stan, Radu V., de Juan Sanz, Jaime, Ryan, Timothy A., Higgs, Henry N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748994/
https://www.ncbi.nlm.nih.gov/pubmed/29142021
http://dx.doi.org/10.1083/jcb.201709111