ER–mitochondria contacts: Actin dynamics at the ER control mitochondrial fission via calcium release

The formin-like protein INF2 is an important player in the polymerization of actin filaments. In this issue, Chakrabarti et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201709111) demonstrate that INF2 mediates actin polymerization at the endoplasmic reticulum (ER), resulting in increased ER...

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Detalles Bibliográficos
Autores principales: Steffen, Janos, Koehler, Carla M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748997/
https://www.ncbi.nlm.nih.gov/pubmed/29259094
http://dx.doi.org/10.1083/jcb.201711075
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author Steffen, Janos
Koehler, Carla M.
author_facet Steffen, Janos
Koehler, Carla M.
author_sort Steffen, Janos
collection PubMed
description The formin-like protein INF2 is an important player in the polymerization of actin filaments. In this issue, Chakrabarti et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201709111) demonstrate that INF2 mediates actin polymerization at the endoplasmic reticulum (ER), resulting in increased ER–mitochondria contacts, calcium uptake by mitochondria, and mitochondrial division.
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spelling pubmed-57489972018-07-02 ER–mitochondria contacts: Actin dynamics at the ER control mitochondrial fission via calcium release Steffen, Janos Koehler, Carla M. J Cell Biol Commentary The formin-like protein INF2 is an important player in the polymerization of actin filaments. In this issue, Chakrabarti et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201709111) demonstrate that INF2 mediates actin polymerization at the endoplasmic reticulum (ER), resulting in increased ER–mitochondria contacts, calcium uptake by mitochondria, and mitochondrial division. The Rockefeller University Press 2018-01-02 /pmc/articles/PMC5748997/ /pubmed/29259094 http://dx.doi.org/10.1083/jcb.201711075 Text en © 2018 Steffen and Koehler http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Steffen, Janos
Koehler, Carla M.
ER–mitochondria contacts: Actin dynamics at the ER control mitochondrial fission via calcium release
title ER–mitochondria contacts: Actin dynamics at the ER control mitochondrial fission via calcium release
title_full ER–mitochondria contacts: Actin dynamics at the ER control mitochondrial fission via calcium release
title_fullStr ER–mitochondria contacts: Actin dynamics at the ER control mitochondrial fission via calcium release
title_full_unstemmed ER–mitochondria contacts: Actin dynamics at the ER control mitochondrial fission via calcium release
title_short ER–mitochondria contacts: Actin dynamics at the ER control mitochondrial fission via calcium release
title_sort er–mitochondria contacts: actin dynamics at the er control mitochondrial fission via calcium release
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748997/
https://www.ncbi.nlm.nih.gov/pubmed/29259094
http://dx.doi.org/10.1083/jcb.201711075
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